Testing announcement
EXPERTISE INFORMATION
Research Group
Areas of Interest
Multidrug resistance mechanism and therapeutic strategies against S. aureus
Dr. Santosh Kumar Sahu
Associate professor, Biotechnology
Ph.D., Biotechnology, M. Sc., Zoology
drsantoshnou@gmail.com
9178939281
20
Publication
Publication
3
Sponsored Projects
Sponsored Projects
Doctoral Students
6
Courses Taught
Courses Taught
PERSONAL INFORMATION
| Course | Year | University |
|---|---|---|
| Ph.D., Biotechnology | 2010 | Department of Biotechnology, Indian Institute of Technology, Madras (IIT Madras) |
| M. Sc., Zoology | 2004 | Department of Zoology, Utkal University, Bhubaneswar |
| B.Sc., (Zoology, Chemistry, Botany) (Zoology Hons) | 2002 | Department of Zoology, Dhenkanal College, Utkal University |
| 10+2 | 1999 | Council of Higher Secondary Education, Odisha |
| 10th | 1997 | Board of Secondary Education, Odisha |
| Position | Institute | Duration |
|---|---|---|
| Associate professor | Dept of Biotechnology, MSCBU | August 2024 to present |
| Assistant professor | Dept of Biotechnology, MSCBU | July 2012-Aug-2023 |
| Research Associate (DST-PURSE) | P.G. Department of Zoology, Utkal University, Vanivihar, Bhubaneswar | 31/03/2012 to 04/07/2012 |
| DBT-Research Associate | Center for Cellular and Molecular Biology, Hyderabad, India | (03/01/2011 to 03/01/2012 |
| Postdoctoral fellow | Weill Cornell Medical College, Cornell University, New York, USA | 15/03/2010 to 31/12/2010 |
| Title | Funding Agency | Amount | Duration | Completed / Ongoing |
|---|---|---|---|---|
| Purification and Characterization of mercuric reductase (Mer A) from highly mercury resistant, biofilm forming bacterial strains isolated from mercury-enriched industrial wastes of Odisha | DST, Govt. of Odisha | 8.51 Lakhs | 3 years | Completed |
| Synthesis of Novel Therapeutic Phyto-conjugates against Multi-drug Resistant S. aureus from flippase inducing Phytochemicals of Gymnema sylvestre and natural anti-S. aureus prodrugs” | DST, Govt. of Odisha | 9.96 Lakh | 3 years | Ongoing |
| Purification and characterization of the resistance factor from Nyctanthes arbortristis that stimulates membrane lipid modification-induced drug resistance in S. aureus | DST, Govt. of India | 30 Lakh | 3years | Ongoing |
| Paper Code | Paper Name | Teaching Years |
|---|---|---|
| BT102 | Biochemistry | 2012-2026 |
| BT202 | Enzymology | 2012-2026 |
| BT301 | Genetic Engineering | 2012-2026 |
| BT206 (OE) | Rdna Technology | 2020-2026 |
| BT402 | Bioethics, Biosafety And Bio-enterpreneurship Development | 2020-2026 |
| Certificate Course | Clinical Biochemistry And Molecular Diagnostics | 2022-2026 |
| Type: M.Phil. / Ph.D. | Title | Enrolled Year | Graduated Year | Role: Supervisor /Co-Supervisor |
|---|---|---|---|---|
| Jesus Ray R.N. :13001N15008 | Biochemical studies on phospholipase activity of total venom from eastern Indian viper (Daboia russelli) | 2015 | 05/05/2016 | Co-Supervisor |
| Susmita Pati R.N.:M16101N15003 | Screening of Anticancer activity potential of Selected Medicinal Plants of Odisha and Evaluation of their Cytotoxic Potential on Malignant Cells | 2015 | 26/09/2016 | Supervisor |
| Sibani Pal R.N.:M16101N16003 | Production of industrially important enzymes from mercury tolerant soil bacteria | 2016 | 01/09/2017 | Supervisor |
| Rashmi Shee R.N: M16101N170010 | Evaluation of the antimicrobial potential of Nyctanthes arbor-tristis and Gymnema sylvestre against heavy metal and membrane mediated drug resistance in bacteria | 2017 | 31/08/2019 | Supervisor |
| Upasana Sahoo, R.N: M16101N18009 | Characterization of phospholipase activity in a Hg2+-tolerant Klebsiella pneumonaie | 2018 | 16/08/2019 | Supervisor |
| Swastisarita Shaw, M16101N19006 | Studies on Flippase-mediated drug resistance in “Staphylococcus aureus” | 2019 | 17/03/2021 | Supervisor |
| Swagatika Dehury M16101N20002 | Characterization of antibiotic resistance mechanism in “Staphylococcus aureus” strain MTCC3160 | 2020 | 26/04/2022 | Supervisor |
| Award Name | Awarding Institute | Award Year |
|---|---|---|
| Joint CSIR-UGC Junior Research Fellowship (JRF) and Eligibility for Lectureship-National Eligibility Test (NET) , December 2003 and June 2004. | CSIR, INDIA | 2003 |
| Joint CSIR-UGC Junior Research Fellowship (JRF) and Eligibility for Lectureship-National Eligibility Test (NET), June 2004 | CSIR, INDIA | 2004 |
| Research Associate-ship at Weill Cornell Medical College, NewYork, USA- | WCMC, CORNELL UNIVERSITY, NEWYORK | 2010 |
| JC Bose fellowship at Center for Cellular and Molecular Biology, Hyderabad, India | DBT, INDIA | 2011 |
| DBT-Research Associate-ship, DBT-India, July, 2011 | DBT, INDIA | 2012 |
| Position | From | To |
|---|---|---|
| Life member (Regd No. 326), Proteomics Society of India | 15/03/2016 | to present |
| Life member (No. 230), Zoological Society of Orissa | 30/03/2022 | to present |
Books Chapter Authored (count) : 03
Book Chapter
- S. N. Gummadi, D. S. Kumar, S. S. Dash, S. K. Sahu, Industrially important carbohydrate degrading enzymes from yeasts: pectinases, chitinases and β-1,3-glucanases, Yeast biotechnology: diversity and applications, DOI: 10.1007/978-1-4020-8292-4_30, Springer Netherlands, Dordrecht,, (2009), Chapter 30, Online ISBN: 978-1-4020-8292-4, print ISBN:978-1-4020-8291-7, p. 673-691.,
- H.G. Behuria, N.S. Pal, R.N. Munda and S.K. Sahu, Preparation of giant unilammelar vesicles (GUVs) from bacterial polar lipid extract: Developing a prokaryotic model membrane system, Biotechnology for sustainable utilization of Bioresources, Astral International Pvt. Ltd, New Delhi, 2019, ISBN:978-93-88982-00-9 (HB), Chapter 28, pp 309-320
- S. K. Sahu and H. G. Behuria, Heavy Metal Toxicity and Their Bioremediation Using Microbes, Plants, and Nanobiomaterials, Bioresource Utilization and Management: Applications in therapeutics, Biofuels, Agriculture and Environmental Science, ISBN: 9781771889339, Apple Academic Press, InC, Canada, Chapter 20, pp 457-470, 2021, DOI: 10.1201/9781003057826-24
JOURNAL
- S. K. Sahu, S. N. Gummadi, N. Manoj, G. K. Aradhyam, Scramblases: an overview, Archives of Biochemistry and Biophysics 462 (2007) 103-114. (2022), ISSN: 0003-9861
- S. K. Sahu, S. N. Gummadi, A. Gopalakrishna, Over-expression of recombinant human phospholipid scramblase 1 in E. coli and its purification from inclusion bodies, Biotechnology Letters 37 (2008) 2131-2137. (3106), IF: 2.154, ISSN: 0141-5492
- S. K. Sahu and S. N. Gummadi, Flippase activity in proteoliposomes reconstituted with Spinacea oleracea endoplasmic reticulum membrane proteins: evidence for biogenic membrane flippase in plants, Biochemistry 47 (2008) 10481-10490. (2884), ISSN: 0006-2960, IF: 2.952
- S. K. Sahu, S. N. Gummadi, A. Gopalakrishna, Calcium binding studies of peptides of human phospholipid scramblases 1 to 4 suggest that scramblases are new class of calcium binding proteins in the cell, Biochemica et Biophysica Acta 1790 (2009) 1274-128. (2741), IF: 3.67, ISSN: 0304-4165
- S. K. Sahu, A. Rajasekharan, S. N. Gummadi, GroES and GroEL are essential chaperones for folding of recombinant human phospholipid scramblase1 in E. coli, Biotechnology Letters 31 (2009) 1745-52. (3106), IF: 2.154, ISSN: 0141-5492
- B. Sahoo, S. K. Sahu, T. Swarnkar, Prediction of sub-cellular localization of scramblase protein family, International Journal of Computer & Communication Technology (2010) 79-87, ISSN: 0975-7449
- S. K. Sahu, R. Saxena, A. Chattopadhyay, Cholesterol depletion modulates detergent resistant fraction in plasma membrane leading to reduction of serotonin1A receptor, Molecular Membrane Biology 29 (2012) 290-298. (17890), IF: 1.647, ISSN: 0968-7688
- S. K. Sahu, H. G. Behuria, S. Gupta, B. Sahoo, Sequence analysis of plasma membrane proteins containing CXXC motif, International Journal of Knowledge Discovery in Bioinformatics 5 (2015) 1-15. (10995), ISSN: 1947-9115
- D. Nandi, S. R. Mishra, C. K. Sahu, S. K. Sahu, Ground water quality in industrial belts of Balasore, International Journal of Earth and Atmospheric Sciences (2015) 2, 16-19, ISSN: 2349-9222
- S. K. Sahu et al., Biochemical characterization of high mercury tolerance in Pseudomonas spp., American Journal of Current Microbiology 4 (2016) 41-54, ISSN: 2572-5815
- S. K. Sahu et al., Cobalt-induced cytotoxicity in E. coli mediated by phospholipid modulation, Journal of Advanced Microbiology 5 (2016) 215-223, ISSN: 2349-7785
- H. G. Behuria et al., Evaluation of mercury tolerant Klebsiella pneumoniae, Journal of Applied Microbiology and Biochemistry 2 (2018) 1-7, ISSN: 2576-1412
- S. K. Sahu, H. G. Behuria, H2O2-induced oxidative stress in E. coli, Journal of Applied Microbiology and Biochemistry 2 (2018) 3:10, ISSN: 2576-1412
- S. K. Sahu et al., Copper and iron overload protect E. coli from H2O2, Environmental Sustainability 2 (2019) 23-32, ISSN: 2523-8922
- H. G. Behuria, B. K. Biswal, S. K. Sahu (2020), Electroformation of liposomes, Journal of Liposome Research, DOI: 10.1080/08982104.2020.1800729, IF: 2.9
- H. G. Behuria, S. K. Sahu, Antimicrobial terpenoid fraction from Gymnema sylvestre, Applied Biochemistry and Biotechnology (2020), IF: 2.3
- U. K. Panigrahi et al., ZnO nanoparticles bioactivity, Nano Express 2 (2021) 010012
- H. G. Behuria et al., Antimicrobial phytochemicals and membrane permeability, ACS Omega (2021), IF: 3.7
- H. G. Behuria et al., Phospholipid scramblases in cancer, Frontiers in Genetics (2022), IF: 4.6
- S. Gupta et al., Purification of alkaline phosphatase, Protein Expression and Purification (2023), IF: 1.7
- G. Panda et al., Bacterial membrane role in phytotherapeutics, MDPI Membranes (2022), IF: 4.56
- A. Khatua et al., Cerium-doped MgO nanoparticles antimicrobial study, Journal of Functional Biomaterials (2023), IF: 4.9
- A. Kumar et al., Carbon dots for antibacterial activity, Colloids and Surfaces A (2023)
- T. Mohanta et al., N,S-doped carbon dots for detection, Analyst (2023)
- G. Panda et al., Lipid flip-flop in MRSA, Archives of Biochemistry and Biophysics (2025)
- S.K. Sahu, Science, society and evolution of scientific attitude in human, Alumni Meet-2017, DOI: 10.28921/nrme.sc.1.2017.120, New Madras Education, Pvt., Ltd., ISBN: 978-81-934044-6-1, pp: 11-16
- S. K. Sahu, Scientiic attitude of ignited minds, Alumni meet 2025, Dept. of Biotechnology, MSCBU, Newredmars Education, ISBN: 978-93-63620-xxx, pp: 11-14, DOI: http://doi.org/:10.28921/nrme.book.AM2025.1.247
- H. G. Behuria, G. Panda and S. K. Sahu, Evaluation of Antimicrobial Potential of Nyctanthes arbor-tristis Leaf Extracts, Biodiversity Conservation and Livelihood Management, ISBN 978-93-90435-13-5, Daya Publishing House® A Division of Astral International Pvt. Ltd., New Delhi – 110 002, 2021, Chapter 20, pp: 245-253
- H. G. Behuria, G. Panda and S. K. Sahu, Electroformation of giant unilamellar vesicles from bacterial polar lipid extract using copper electrode, Green Technology for Environment Management, Daya Publishing House®, Astral International Pvt Ltd, NewDelhi-110002, ISBN:978-93-5461-379-1, chapter 15, pp 185-191
- Panda, G., sahu,S.K., Natural Product Mediated Therapeutic Application of Artificial Membrane Models: An Insight, Communities, Biodiversity and Conservation of Similipal, 2025, Daya Publishing House®, A Division of Astral International Pvt. Ltd, New Delhi – 110 002, ISBN: 978-93-5919-453-0, Pages: 189-204